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pentobarbital will lessen the level or result of rolapitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Prolonged-phrase coadministration of sturdy CYP3A4 inducers with rolapitant might noticeably lower rolapitant efficacy.Phenytoin and barbiturate blood amounts needs to be monitored a lot more rou